Viagra Research Today is a free monthly online journal that collates and summarizes the latest research about Viagra, including details on sildenafil, erectile dysfunction, impotence, side-effects, alternatives.

Structure determination of a sildenafil analogue contained in commercial herb drinks.

Shin C, Hong M, Kim D, Lim Y

Bio/Molecular Informatics Center, Konkuk University, Hwayang-Dong 1, Kwangjin-Ku, Seoul 143-701, Korea.

It was found from HPLC analysis that a commercial herb drink contains a putative sildenafil analog. In order to identify the sildenafil-like compound, separation and purification were carried out. The structure determination was performed based on routine 1D and 2D NMR experiments. Unlike sildenafil, the compound contains an ethylpiperazine instead of a methylpiperazine group. In addition, the piperazine and phenyl groups are connected through an acetyl group instead of the sulfonyl group of sildenafil.

Published 16 November 2004 in Magn Reson Chem, 42(12): 1060-2.
Full-text of this article is available online (may require subscription).

© 2004-2008 Viagra Research Today. All Rights Reserved.