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Sildenafil in pulmonary hypertension secondary to unilateral agenesis of pulmonary artery.

Hamdan MA, Abu-Sulaiman RM, Najm HK

Section of Pediatric Cardiology, King Abdulaziz Cardiac Center, King Fahad National Guard Hospital, Riyadh, Saudi Arabia.

Unilateral agenesis of the pulmonary artery (PA) is a rare anomaly that can lead to pulmonary hypertension (PHTN). We report the case of a 10-month-old female with agenesis of the left PA, ventricular septal defect, and patent ductus arteriosus who developed PHTN precluding surgical repair. The use of sildenafil decreased PA pressure and normalized pulmonary vascular resistance, after which surgery was successfully performed.

Published 21 March 2006 in Pediatr Cardiol, 27(2): 279-81.
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