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Effects of sildenafil on blue-on-yellow and white-on-white Humphrey perimetry in 3 months regular use.

Dündar SO, Topalo Gcaron Lu A, Dündar M, Koçak I

Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, Aydin, Turkey. orucs@yahoo.com

PURPOSE: To assess the effects of sildenafil on blue-on-yellow (B/Y) and white-on-white (W/W) Humphrey perimetry in a group of men with erectile dysfunction in 3 months regular use. METHODS: In this prospective study, 14 patients with erectile dysfunction received 50 mg doses of sildenafil (Viagra, Pfizer) two times per week regularly for 3 months. Patients underwent best-corrected visual acuity (BCVA), colour vision, anterior segment and fundus examination, and B/Y and W/W Humphrey perimetry in each eye before and after sildenafil treatment. Changes in mean deviations (MD) were compared separately for both eyes. RESULTS: No significant changes from baseline were observed in BCVA and colour vision after sildenafil treatment. The anterior segment and fundus examinations revealed no abnormalities. There was no change on B/Y and W/W Humphrey visual field. MD values of B/Y and W/W Humphrey perimetry remained nonsignificant for both eyes after 3 months regular use of sildenafil (P=0.133, and 0.092, respectively, for right, and P=0.221 and 0.925, respectively, for left eyes). CONCLUSION: Oral sildenafil used regularly for 3 months produced no effect on B/Y and W/W Humphrey perimetry.

Published 6 July 2006 in Eye, 20(7): 810-3.
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