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Bosentan and sildenafil: should the combination therapy be a valid alternative in childhood to prostacyclin infusion?

Brancaccio G, Toscano A, Bevilacqua M, Di Chiara L, Parisi F

Department of Pediatric Cardiology and Cardiac Surgery, Ospedale Pediatrico Bambino Gesù, Rome, Italy. gbrancaccio70@hotmail.com

We report a case of a seven-yr-old girl with a PAH treated with continuation therapy of bosentan and sildenafil. The combination therapy revealed safety and efficacy in long-term follow up.

Published 22 January 2007 in Pediatr Transplant, 11(1): 110-2.
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