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In vitro sildenafil citrate use as a sperm motility stimulant.

Mostafa T

Andrology & Sexology Department, Faculty of Medicine, Cairo University, Cairo, Egypt. taymour1155@link.net

The effect of different concentrations of sildenafil citrate (Viagra) solution in vitro on human sperm motility was assessed in 85 asthenozoospermic semen specimens. Semen samples were divided equally into six tubes, one as a control and to the others, sildenafil dissolved solution was added (v/v) in vitro with five different concentrations (4.0, 2.0, 1.0, 0.5, 0.1 mg/mL). The tubes were incubated and were followed up for sperm motility changes at 0.5, 1, 2, and 3 hours. It is demonstrated that the in vitro use of sildenafil citrate solution has a concentration-related stimulatory effect on ejaculated sperm motility.

Published 8 October 2007 in Fertil Steril, 88(4): 994-6.
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