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Sildenafil Use in a Symptomatic Neonate with Severe Ebstein's Anomaly of the Tricuspid Valve.

Aggarwal S, Chintala K, Humes RA

Division of Cardiology, The Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit, Michigan.

Ebstein's anomaly (EA) is associated with poor outcome in symptomatic neonates. Management typically includes prostaglandins or surgical creation of a Blalock-Taussig shunt. Right ventricular afterload reduction may help by improving the forward flow across the pulmonary valve. We report the successful use of oral sildenafil, a pulmonary vasodilator, in a neonate with severe EA.

Published 14 February 2008 in Am J Perinatol, 25(2): 125-8.
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